еКорпус – библиографски запис
Заступљеност морфина као метаболита хероина у ткиву постељице и плода – приказ случаја
The Presence of Morphine as Heroin Metabolites in Placental Tissue and Fetus: Case Report
- Часопис
- Serbian Archives of Medicine
- Објављено
- Srp Arh Celok Lek. 2014;142(9–10):610–613.
- Врста рада
- CASE REPORTS
Abstract
Introduction Females who have developed addiction to heroin also abuse it during pregnancy. Heroin can be detected in the fetal blood-flow already an hour after maternal i.v. injection. Heroin metabolites enter the fetal blood-flow through the placental barrier by passive transport.
Case Outline We present a 27-year-old female in the 5th month of pregnancy that had a miscarriage. Chemo-toxicological analysis (gas chromatography with mass spectrometry – GC/MS), showed the presence of morphine in the fetal liver (31.92 ng/g), placenta (27.94 ng/g) and meconium (136.33 ng/g). The analysis did not show the presence of 6-monoacetylmorphine.
Conclusion In all cases when the autopsy of fetus or newborn is performed, with mother suspected as i.v. heroin abuser, chemo-toxicological placental analysis, placenta and meconium should be also done
Keywords: heroin; morphine; placenta; meconium; autopsy