Ankyloblepharon filiforme adnatum with a bilateral cleft lip and palate

Abstract

Introduction Ankyloblepharon filiforme adnatum (AFA) is a rare congenital abnormality of the eyelids that has been reported as an isolated anomaly, but may also be associated with other anomalies or as a part of well-defined syndromes. The aim of this work was to present a case of familial AFA associated with bilateral cleft lip and palate.

Case outline A full-term female newborn (40 weeks’ GA, BM 3,700 g) had bilateral partially fused eyelids at birth, associated with a cleft lip and palate. The surgical treatment was performed five days after AFA was diagnosed. The baby’s mother also had AFA, without a cleft lip or palate. The baby girl has been followed-up by a plastic surgeon, a specialist in orthodontics, as well as an ophthalmologist and a pediatrician.

Conclusion This case indicates familial clustering of AFA, whereby it assumes a more severe form in the following generation. A cleft lip and palate in our patient has required surgical treatment, oral and dental rehabilitation, as well as the need for more intensive care and regular follow-ups by multidisciplinary teams.

Keywords: newborn; eyelids; congenital abnormality; cleft lip and palate