УЛОГА ИМУНСКИХ ФАКТОРА У ПАТОГЕНЕЗИ СЕКРЕЦИОНОГ ОТИТИСА МЕДИЈА

Abstract

Authors have been analysed the main role of immunological factors in complex pathogenesis of secretory otitis media. Data from recent literature and data from studies that were conducted in ENT city hospital in Belgrade were rewievied. The mucosa of the middle esr belong to the nasopharyngeal associated lymphoid tissue (NALT). The factors of the specific and non specific mucosal deffence in middle ear mucosa can influence the mechanism of the chronic inflammation in secretory otitis media. The role of macrophages, mast cells, lymphoplasmocytes and adhesion molecules was ephasized. Concerning that results it is possible to create clinical stydies in order improove the diagnostic procedures ant therapy of secretory otitis media.

Keywords: secretory otitis media, immunopathogenesis.