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НОВЕ СТРАТЕГИЈЕ У ЛЕЧЕЊУ СИНДРОМА МУЛТИПЛЕ ОРГАНСКЕ ДИСФУНКЦИЈЕ У СЕПСИ
NEW STRATEGIES IN MULTIPLE ORGAN DYSFUNCTION SYNDROME THERAPY FOR SEPSIS
- Часопис
- Serbian Archives of Medicine
- Објављено
- Srp Arh Celok Lek. 2005;133(7–8):379–383.
- Врста рада
- REVIEW ARTICLES
Abstract
Despite more than 20 years of extensive research, sepsis and/or trauma induced multiple organ dysfunction syndrome (MODS) remain the chief cause of death in intensive care units, with mortality rates between 30% and 80%. Early goal-direct‑ ed therapy (EGDT), use of drotrecogin alfa (activated), tight control of hyperglycaemia, and adrenal replacement therapy (low doses of corticosteroids), all constitute new treatment strategies. In future, a combination of therapies should be individually adjusted for each patient.
Keywords: sepsis; MODS; EGDT; drotrecogin alfa