МАТЕМАТИЧКИ МОДЕЛ У ПРЕДИКЦИЈИ УТИЦАЈА ХИПЕРЛИПИДЕМИЈЕ НА ДЕБЉИНУ КОМПЛЕКСА ИНТИМОМЕДИЈЕ ЗИДА КАРОТИДНИХ АРТЕРИЈА КАО ПОКАЗАТЕЉА АТЕРОСКЛЕРОЗЕ

Abstract

The growth of intima media complex is widely accepted parameter in studies that are in relation to the process of atherosclerosis. Increased value of intima-media thickness (IMT) a. carotis communis is the incontestable index of atherosclerosis process in regard to distinct vascular spheres and wider cardiovascular risk. Hypercholesterolemia as the well-known promoter of atherogenesis influence on the increase of IMT. It is established that there is a highly valuable connection (p < 0.001) between the levels of cholesterol and the thickness of IMT. It is also observed a highly significant linear and cubic correlation between the cholesterol and IMT. Concerning the relationship between trigliceride and IMT, it stands out as the highly relevant (R = 0.42; p < 0.001) but the coefficient of correlation is fewer than cholesterol (R = 0.56). Increased value of cholesterol and triglicerides exerts influence on IMT of a. carotis communis simultaneously which leads to highly consequential equation: IMT = 0.005 × TG – 0.008 × Chol + 0.28. This mathematics model can be noteworthy if one anticipates effects of primary and secondary prevention.

Keywords: A. carotis communis, thickness of intima-media, mathematics model, prediction of atherosclerosis.