РОЗАЦЕА КАО МУЛТИСИСТЕМСКА БОЛЕСТ

Abstract

Rosacea is a chronic skin disorder, affecting the face and chest, and develops mostly in the 3ʳᵈ to 6ᵗʰ decades of life. It is caracterized by erythema, telangiectasias, and reccurent flushings. During the time of this chronic inflamation, skin tipically develops papules, pustules, and swelling. Ocular involvement occurs in 3 to 58 % of patients with skin changes. Common ocular signs include blepharoconjunctivitis, meibomitis, and dry eyes. Rosacea keratitis, when present, however, has a poor prognosis and may lead to blindness. Among skin diseases, Helicobacter pylori infection has been often related with rosacea. A higher prevalence of indigestion and Helicobacter pylori infection in rosacea patients than in healthy controls has been reported. However, no causal relation has been identified. On the other hand, oral treatment with metronidazole is beneficial in all of three mentioned manifestations of rosacea (skin, eye, indigestion). There is obvious need for multidiscuplinary approach, and investigation to rosacea.

Keywords: rosacea, eye, gastrointestinal tract, Helicobacter pylori.