Successfully completed pregnancy after conservative treatment of nonepithelial ovarian cancer

Abstract

Introduction Granulosa cell tumors are rare neoplasms of the ovary with low malignancy potential and late recurrence. They originate from the granulose of the ovary stromal cells and have the ability to produce estrogen. The main treatment is surgical and implies hysterectomy with bilateral salpingo-oophorectomy, omentectomy, taking peritoneal biopsies, and cytological analysis of the peritoneal washing. When found in young women who have not given birth, a conservative approach can be considered. Fertility sparing surgery is safe only for early FIGO (Fédération Internationale de Gynécologie et d’Obstétrique) stages IA tumors to IC, where it is necessary to make unilateral salpingo-oophorectomy and complete staging.

Case outline We present a case of young woman with granulosa cell tumor who was accidentally discovered, and after an adequate surgery and chemotherapy she gave a birth to a healthy child.

Conclusion Young women who have not given birth and who have been diagnosed with granulosa cell ovarian tumor can be treated conservatively after adequate disease staging and confirmation that the disease is at an early stage.

Keywords: ovarian granulosa cell tumor; fertility sparing surgery in granulosa cell tumors, treatment; prognostic factors; monitoring