IgA НЕФРОПАТИЈА: КЛИНИЧКО-МОРФОЛОШКА КОРЕЛАЦИЈА

Abstract

IgA nephropathy is glomerular disease caracterized by the presence of IgA dominant or codominant imunoglobuline deposits in glomerular mesangium which can be demostrated by immunofluorescence. Clinical manifestations of IgA nephropathy in the majority of cases is hematuria which can be macro or mikroskopic, isolated or combined with proteinuria, which can be of nephrotic range. The prognosis of the disease is better if presented with haematuria. Intensity of morphologic changes as wella as the prognosis is in correlation with the amount of proteinuria. The prognosis is better in children.

Keywords: IgA nephropathy, hematuria, proteinuria, renal insuficiency.